Utility of the ceftazidime-imipenem antagonism test (CIAT) to detect and confirm the presence of inducible AmpC beta-lactamases among enterobacteriaceae
Braz. j. infect. dis
;
11(2): 237-239, Apr. 2007. ilus
Artículo
en Inglés
| LILACS
| ID: lil-454725
ABSTRACT
Detection of AmpC beta-lactamase production by enterobacteria has been problematic. Contrary to ESBLs, no specific guidelines are available for detection and confirmation of AmpC production by clinical relevant microorganisms. Moreover, some bacterial species may produce inducible AmpC beta-lactamases that can be easily overlooked by routine susceptibility tests. We reported here a new test based on the strong inducible effect of imipenem on AmpC genes and the consequent antagonism with ceftazidime. This test is very simple and proved to be helpful in detecting AmpC-inducible enzymes among several species of clinical isolates.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Proteínas Bacterianas
/
Beta-Lactamasas
/
Ceftazidima
/
Imipenem
/
Enterobacteriaceae
/
Antibacterianos
Tipo de estudio:
Guía de Práctica Clínica
Límite:
Humanos
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2007
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Weinmann Laboratório LTDA/BR
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