Immunoelectronic localization of myosin-Va in rat cerebellum
Braz. j. morphol. sci
;
22(4): 211--214, Oct.-Dec. 2005. ilus
Artículo
en Inglés
| LILACS
| ID: lil-468028
ABSTRACT
Myosin V is an unconventional type of actin-binding myosin that participates in cytoplasmic organelle transport. Although this unconventional myosin has been extensively studied, its subcellular localization in the mammalian cerebellum has not been determined. In this work, we used an antibody against the tail domain of the myosin-Va heavy chain and a secondary antibody labeled with protein A-gold (15 nm) to study the subcellular distribution of this protein. Myosin-Va was found in the cytoplasm, where it was associated with a filament (probably actin). This protein was also detected in the plasma membrane of axons and dendrites in the molecular layer in rat cerebellum.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Células de Purkinje
/
Proteína Estafilocócica A
/
Telencéfalo
/
Miosina Tipo V
/
Fenómenos Fisiológicos del Sistema Nervioso
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. morphol. sci
Asunto de la revista:
Anatomía
Año:
2005
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Federal University of Goiás/BR
/
Federal University of Uberlândia/BR
/
University of Patos de Minas/BR
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