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Clustering of cases of Mycobacterium fortuitum infection investigated by molecular typing
Levett, P. N; Brown, P. D; Hector, S; Scantlebury, M. U; Roach, T. C.
  • Levett, P. N; University of the West Indies. School of Clinical Medicine & Research. BB
  • Brown, P. D; s.af
  • Hector, S; s.af
  • Scantlebury, M. U; s.af
  • Roach, T. C; s.af
West Indian med. j ; 48(1): 16-19, Mar. 1999.
Artículo en Inglés | LILACS | ID: lil-473126
ABSTRACT
Organisms of the Mycobacterium fortuitum complex are recognised but uncommon causes of pulmonary disease, primary cutaneous disease and a wide spectrum of nosocomial infections. M fortuitum was isolated from 20 patients over a 15 month period, with an apparent clustering of isolates occurring from January to March 1994. The molecular epidemiology of this clustering was investigated using an arbitrary primer polymerase chain reaction method (AP-PCR). 21 isolates were studied, which yielded 13 distinct profiles. Multiple isolates from a single patient yielded identical profiles. All of seven isolates recovered during the six week period from January to March 1994 shared a common profile which was distinct from all other isolates, suggesting that a single strain was isolated from specimens from all seven patients. The source of this cluster is uncertain. We can find no epidemiological basis for an episode of cross-infection within the hospital environment, and it is assumed that contamination of the specimens during collection, transport or processing was responsible for the [quot ]pseudo-outbreak[quot ] of M fortuitum.
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Índice: LILACS (Américas) Asunto principal: Infección Hospitalaria / Mycobacterium fortuitum / Infecciones por Mycobacterium no Tuberculosas Tipo de estudio: Estudio diagnóstico / Estudio observacional / Factores de riesgo Límite: Humanos Idioma: Inglés Revista: West Indian med. j Asunto de la revista: Medicina Año: 1999 Tipo del documento: Artículo País de afiliación: Barbados Institución/País de afiliación: University of the West Indies/BB

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Índice: LILACS (Américas) Asunto principal: Infección Hospitalaria / Mycobacterium fortuitum / Infecciones por Mycobacterium no Tuberculosas Tipo de estudio: Estudio diagnóstico / Estudio observacional / Factores de riesgo Límite: Humanos Idioma: Inglés Revista: West Indian med. j Asunto de la revista: Medicina Año: 1999 Tipo del documento: Artículo País de afiliación: Barbados Institución/País de afiliación: University of the West Indies/BB