Positron emission tomography with 2-[18F]-fluoro-2-deoxy-D-glucose in the evaluation of postoperative endometrial cancer patients
Rev. med. nucl. Alasbimn j
;
9(37)July 2007. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-474918
ABSTRACT
Objective To evaluate the usefulness of positron emission tomography with 2-[18F]fluoro-2-deoxy-D-glucose (FDG-PET) in the follow-up of endometrial cancer patients with suspicion of recurrence due to elevated serum tumour markers and suggestive conventional imaging findings. Material and methods A retrospective review was conducted of 17 FDG-PET studies performed in 11 patients with a previous diagnosis of endometrial cancer (6 patients underwent 2 studies) between April 2002 and October 2005. Mean age of patients was 63.4 yrs (range, 52-69 yrs), and mean time since diagnosis was 56 months (range, 11 months - 12 yrs). Initially, 7 patients were in stage I, 3 in stage III, and 1 in stage IV (FIGO classification). Histologically, they corresponded to 8 endometrioid and 3 non-endometrioid cancers. Results FDG-PET showed infradiaphragmatic uptake in three patients and disseminated disease in seven; findings were negative in one patient. Computed tomography (CT, n=7) or magnetic resonance (MRI, n=7) images revealed infradiaphragmatic lesions in five patients and visceral lesions in two. All patients showed elevated serum tumour markers (CA125, n=9; CA19.9, n=2; CA15.3, n=2). FDG-PET results modified the information provided by conventional imaging techniques in seven patients and provided no additional information in the remaining four. There was histological confirmation of lesions in two patients. Nine patients were clinically followed up, including imaging studies (mean follow-up, 8.7 months; range, 3-20 months).
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Índice:
LILACS (Américas)
Asunto principal:
Neoplasias Uterinas
/
Adenocarcinoma
/
Tomografía Computarizada de Emisión
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Neoplasias Endometriales
/
Carcinoma Adenoescamoso
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Rev. med. nucl. Alasbimn j
Asunto de la revista:
Medicina Nuclear
Año:
2007
Tipo del documento:
Artículo
País de afiliación:
España
Institución/País de afiliación:
University Hospital Virgen de las Nieves/ES
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