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Difficulties reported by hiv-infected patients using antiretroviral therapy in brazil
Guimarães, Mark Drew Crosland; Rocha, Gustavo Machado; Campos, Lorenza Nogueira; Freitas, Felipe Melo Teixeira de; Gualberto, Felipe Augusto Souza; Teixeira, Ramiro d'Ávila Rivelli; Castilho, Fábio Morato de.
  • Guimarães, Mark Drew Crosland; Federal University of Minas Gerais. Faculty of Medicine. Department of Preventive and Social Medicine. Belo Horizonte. BR
  • Rocha, Gustavo Machado; Federal University of Minas Gerais. Faculty of Medicine. Department of Preventive and Social Medicine. Belo Horizonte. BR
  • Campos, Lorenza Nogueira; Federal University of Minas Gerais. Faculty of Medicine. Department of Preventive and Social Medicine. Belo Horizonte. BR
  • Freitas, Felipe Melo Teixeira de; Federal University of Minas Gerais. Faculty of Medicine. Department of Preventive and Social Medicine. Belo Horizonte. BR
  • Gualberto, Felipe Augusto Souza; Federal University of Minas Gerais. Faculty of Medicine. Department of Preventive and Social Medicine. Belo Horizonte. BR
  • Teixeira, Ramiro d'Ávila Rivelli; Federal University of Minas Gerais. Faculty of Medicine. Department of Preventive and Social Medicine. Belo Horizonte. BR
  • Castilho, Fábio Morato de; Federal University of Minas Gerais. Faculty of Medicine. Department of Preventive and Social Medicine. Belo Horizonte. BR
Clinics ; 63(2): 165-172, 2008. tab
Artículo en Inglés | LILACS | ID: lil-481044
ABSTRACT

OBJECTIVE:

To describe the degree of difficulty that HIV-infected patients have with therapy treatment.

INTRODUCTION:

Patients’ perceptions about their treatment are a determinant factor for improved adherence and a better quality of life.

METHODS:

Two cross-sectional analyses were conducted in public AIDS referral centers in Brazil among patients initiating treatment. Patients interviewed at baseline, after one month, and after seven months following the beginning of treatment were asked to classify and justify the degree of difficulty with treatment. Logistic regression was used for analysis.

RESULTS:

Among 406 patients initiating treatment, 350 (86.2 percent) and 209 (51.5 percent) returned for their first and third visits, respectively. Treatment perceptions ranged from medium to very difficult for 51.4 percent and 37.3 percent on the first and third visits, respectively. The main difficulties reported were adverse reactions to the medication and scheduling. A separate logistic regression indicated that the HIV-seropositive status disclosure, symptoms of anxiety, absence of psychotherapy, higher CD4+ cell count (> 200/mm³) and high (> 4) adverse reaction count reported were independently associated with the degree of difficulty in the first visit, while CDC clinical category A, pill burden (> 7 pills), use of other medications, high (> 4) adverse reaction count reported and low understanding of medical orientation showed independent association for the third visit.

CONCLUSIONS:

A significant level of difficulty was observed with treatment. Our analyses suggest the need for early assessment of difficulties with treatment, highlighting the importance of modifiable factors that may contribute to better adherence to the treatment protocol.
Asunto(s)

Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Calidad de Vida / Infecciones por VIH / Cooperación del Paciente / Fármacos Anti-VIH / Accesibilidad a los Servicios de Salud Tipo de estudio: Ensayo Clínico Controlado / Estudio de etiología / Guía de Práctica Clínica / Estudio observacional / Estudio de prevalencia / Estudio pronóstico / Factores de riesgo Límite: Adolescente / Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: Clinics Asunto de la revista: Medicina Año: 2008 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Federal University of Minas Gerais/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Calidad de Vida / Infecciones por VIH / Cooperación del Paciente / Fármacos Anti-VIH / Accesibilidad a los Servicios de Salud Tipo de estudio: Ensayo Clínico Controlado / Estudio de etiología / Guía de Práctica Clínica / Estudio observacional / Estudio de prevalencia / Estudio pronóstico / Factores de riesgo Límite: Adolescente / Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: Clinics Asunto de la revista: Medicina Año: 2008 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Federal University of Minas Gerais/BR