Difficulties reported by hiv-infected patients using antiretroviral therapy in brazil
Clinics
;
63(2): 165-172, 2008. tab
Artículo
en Inglés
| LILACS
| ID: lil-481044
ABSTRACT
OBJECTIVE:
To describe the degree of difficulty that HIV-infected patients have with therapy treatment.INTRODUCTION:
Patients perceptions about their treatment are a determinant factor for improved adherence and a better quality of life.METHODS:
Two cross-sectional analyses were conducted in public AIDS referral centers in Brazil among patients initiating treatment. Patients interviewed at baseline, after one month, and after seven months following the beginning of treatment were asked to classify and justify the degree of difficulty with treatment. Logistic regression was used for analysis.RESULTS:
Among 406 patients initiating treatment, 350 (86.2 percent) and 209 (51.5 percent) returned for their first and third visits, respectively. Treatment perceptions ranged from medium to very difficult for 51.4 percent and 37.3 percent on the first and third visits, respectively. The main difficulties reported were adverse reactions to the medication and scheduling. A separate logistic regression indicated that the HIV-seropositive status disclosure, symptoms of anxiety, absence of psychotherapy, higher CD4+ cell count (> 200/mm³) and high (> 4) adverse reaction count reported were independently associated with the degree of difficulty in the first visit, while CDC clinical category A, pill burden (> 7 pills), use of other medications, high (> 4) adverse reaction count reported and low understanding of medical orientation showed independent association for the third visit.CONCLUSIONS:
A significant level of difficulty was observed with treatment. Our analyses suggest the need for early assessment of difficulties with treatment, highlighting the importance of modifiable factors that may contribute to better adherence to the treatment protocol.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Calidad de Vida
/
Infecciones por VIH
/
Cooperación del Paciente
/
Fármacos Anti-VIH
/
Accesibilidad a los Servicios de Salud
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio de etiología
/
Guía de Práctica Clínica
/
Estudio observacional
/
Estudio de prevalencia
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Clinics
Asunto de la revista:
Medicina
Año:
2008
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Federal University of Minas Gerais/BR
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