Cloning and analysis of IFRG (interferon responsive gene) in rabbit oocytes and preimplantation embryos
Biocell
;
31(2): 199-203, ago. 2007. ilus
Artículo
en Inglés
| LILACS
| ID: lil-491562
ABSTRACT
Although there is more evidence that shows that IFNs (interferons) plays a very important role in the early development of the embryo, the mechanism of IFNs is still unclear. Our study showed that IFRG is expressed from oocytes- through to the preimplantation embryo in rabbits. This finding provides some clues for better understanding the role of IFNs in the development of the embryo. The full length of rabbit IFRG cDNA (Accession No. AJ584672), with a 2794bp encoding 131 amino acid sequence, was cloned IFRG expression can be detected in 8 different tissues ovary, heart, lung, liver, kidney, spleen, cerebra, and the 18-day whole-body embryo. Whole-mount in situ hybridization showed that IFRG was highly expressed in the inner-cell mass of rabbit blastula. IFRG may play an important role in embryo development and tissue differentiation.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Oocitos
/
Blastocisto
/
ARN Mensajero
/
Interferones
/
ADN Complementario
/
Regulación del Desarrollo de la Expresión Génica
Límite:
Animales
Idioma:
Inglés
Revista:
Biocell
Asunto de la revista:
Clulas
Año:
2007
Tipo del documento:
Artículo
País de afiliación:
China
Institución/País de afiliación:
Chinese Academy of Sciences/CN
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