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Cloning and analysis of IFRG (interferon responsive gene) in rabbit oocytes and preimplantation embryos
Qi, B; Zheng, X; Li, W; Wei, Q; Chen, Q.
  • Qi, B; Chinese Academy of Sciences. Laboratory of Molecular and Developmental Biology. Beijing. CN
  • Zheng, X; Chinese Academy of Sciences. Laboratory of Molecular and Developmental Biology. Beijing. CN
  • Li, W; Chinese Academy of Sciences. Laboratory of Molecular and Developmental Biology. Beijing. CN
  • Wei, Q; Chinese Academy of Sciences. Laboratory of Molecular and Developmental Biology. Beijing. CN
  • Chen, Q; Chinese Academy of Sciences. Laboratory of Molecular and Developmental Biology. Beijing. CN
Biocell ; 31(2): 199-203, ago. 2007. ilus
Artículo en Inglés | LILACS | ID: lil-491562
ABSTRACT
Although there is more evidence that shows that IFNs (interferons) plays a very important role in the early development of the embryo, the mechanism of IFNs is still unclear. Our study showed that IFRG is expressed from oocytes- through to the preimplantation embryo in rabbits. This finding provides some clues for better understanding the role of IFNs in the development of the embryo. The full length of rabbit IFRG cDNA (Accession No. AJ584672), with a 2794bp encoding 131 amino acid sequence, was cloned IFRG expression can be detected in 8 different tissues ovary, heart, lung, liver, kidney, spleen, cerebra, and the 18-day whole-body embryo. Whole-mount in situ hybridization showed that IFRG was highly expressed in the inner-cell mass of rabbit blastula. IFRG may play an important role in embryo development and tissue differentiation.
Asunto(s)
Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Oocitos / Blastocisto / ARN Mensajero / Interferones / ADN Complementario / Regulación del Desarrollo de la Expresión Génica Límite: Animales Idioma: Inglés Revista: Biocell Asunto de la revista: C‚lulas Año: 2007 Tipo del documento: Artículo País de afiliación: China Institución/País de afiliación: Chinese Academy of Sciences/CN

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Oocitos / Blastocisto / ARN Mensajero / Interferones / ADN Complementario / Regulación del Desarrollo de la Expresión Génica Límite: Animales Idioma: Inglés Revista: Biocell Asunto de la revista: C‚lulas Año: 2007 Tipo del documento: Artículo País de afiliación: China Institución/País de afiliación: Chinese Academy of Sciences/CN