Optical density of bone repair after implantation of homogenous demineralized dentin matrix in diabetic rabbits
Braz. oral res
;
22(3): 275-280, 2008. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-495605
ABSTRACT
This research evaluated the bone repair process after implantation of homogenous demineralized dentin matrix (HDDM) in surgical defects in the parietal bone of rabbits with alloxan-induced diabetes, using a polytetrafluorethylene (PTFe) barrier for guided bone regeneration. Thirty-six rabbits were used and divided into four groups control (C, n = 12), diabetic (D, n = 12, left parietal bone), diabetic with PTFe (D-PTFe, same 12 rabbits, right parietal bone), and diabetic with PTFe associated to HDDM (D-PTFe+HDDM, n = 12). Bone defects were created in the parietal bone of the rabbits and the experimental treatments were performed, where applicable. The rabbits were sacrificed after 15, 30, 60 and 90 days. The bone defects were examined radiographically and by optical density (ANOVA and Tukey test, p < .05). The radiographic findings showed that the D-PTFe+HDDM group presented greater radiopacity and better trabecular bone arrangement when compared to that of the C, D and D-PTFe groups. The statistical analysis showed significant differences in the optical density of the newly formed bone among the studied groups. It was possible to conclude that HDDM was biocompatible in diabetic rabbits.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Materiales Biocompatibles
/
Regeneración Ósea
/
Densidad Ósea
/
Dentina
/
Regeneración Tisular Dirigida
/
Diabetes Mellitus Experimental
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. oral res
Asunto de la revista:
Odontología
Año:
2008
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Brasil
Institución/País de afiliación:
Pontifical Catholic University of Rio Grande do Sul/BR
/
State University of Campinas/BR
/
São Paulo State University/BR
/
University of Cuiabá/BR
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