Mutagénesis ambiental y el uso de biomarcadores para predecir el riesgo de cáncer: [revisión] / Environmental mutagenesis and use of biomarkers in cancer risk prediction: [review]
Rev. biol. trop
;
52(3): 585-590, sept. 2004.
Artículo
en Español
| LILACS
| ID: lil-501722
ABSTRACT
The field of environmental mutagenesis or toxicology genetics aims to study the genetic damage that leads to mutations produced by physical, chemical and biological agents, to identify these agents and analyze their interactions and ways of action. There are enough experimental and epidemiological evidences implicating mutations in oncogenes, tumor suppressor genes and DNA repair genes as determinants in the onset and progression of the neoplastic process. A valuable tool in public and occupational health is the monitoring of populations exposed to potentially hazardous agents. The objective is to protect the health and quality of life of high risk groups on account of the nature of the agents of exposure. Monitoring of genotoxic effects in exposed populations as well as the analysis of susceptibility polymorphism are visualized as key tools in the realm of future public and occupational health in order to prevent the occurrence of environmental and specially occupational origin of tumors. This paper reviews the main concepts concerning this issue and refers to studies on the subject in Costa Rica.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Carcinógenos Ambientales
/
Biomarcadores
/
Monitoreo del Ambiente
/
Exposición a Riesgos Ambientales
/
Neoplasias
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
País/Región como asunto:
America Central
/
Costa Rica
Idioma:
Español
Revista:
Rev. biol. trop
Asunto de la revista:
Biologia
/
Medicina Tropical
Año:
2004
Tipo del documento:
Artículo
País de afiliación:
Costa Rica
Institución/País de afiliación:
Universidad de Costa Rica/CR
Similares
MEDLINE
...
LILACS
LIS