A study of iga antibody response to different mycobacterium tuberculosis antigens in the diagnosis and monitoring of pulmonary tuberculosis
Braz. j. infect. dis
;
13(1): 53-58, Feb. 2009. graf, tab
Artículo
en Inglés
| LILACS
| ID: lil-517815
ABSTRACT
We evaluated the performance of the ELISA technique in the detection of IgA antibodies against different Mycobacterium tuberculosis antigenic preparations in serum samples from 49 patients with pulmonary tuberculosis collected before and after the start of specific treatment. The controls consisted of serum samples from healthy patients without any prior contact with the bacteria and serum samples from patients with other pneumopathies. Glycolipid antigen gave the best diagnostic performance, with a sensitivity of 88 percent and specificities varying from 88 to 100 percent in the control groups. These antigens constitute a powerful tool for the diagnosis and monitoring of patients with pulmonary tuberculosis.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Tuberculosis Pulmonar
/
Inmunoglobulina A
/
Anticuerpos Antibacterianos
/
Mycobacterium tuberculosis
/
Antígenos Bacterianos
Tipo de estudio:
Estudio diagnóstico
/
Estudios de evaluación
/
Estudio observacional
/
Estudio pronóstico
Límite:
Adolescente
/
Adulto
/
Anciano
/
Humanos
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2009
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Federal University of Maranhão/BR
/
Federal University of Santa Maria/BR
/
São Paulo Institute of Tropical Medicine/BR
/
University of São Paulo/BR
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