Trastorno linfoproliferativo post trasplante renal en un niño / Lymphoproliferative disorders after renal transplantation in a child
Rev. méd. Chile
;
137(3): 405-410, mar. 2009. ilus, tab
Artículo
en Español
| LILACS
| ID: lil-518502
ABSTRACT
Post transplant lymphoproliferative disorder (PTLD) is the commonest form of post transplant malignancy in children. The incidence in renal transplant recipients varies between 2 percent-4 percent. They are characterized by uncontrolled B lymphocyte proliferation, in most cases driven by Epstein Barr virus (EBV). They are more common in younger children, EBV seronegative patients and those who receive aggressive immunosuppression. PTLD commonly presents in an unspecific form and it requires high suspicion rate for its diagnosis, especially in children with risk factors. We report a twelve year-old girl who developed fever, sore throat and lymph node enlargement, six months after receiving a renal allograft. Laboratory assessment and imaging studies were compatible with PTLD, which was confirmed by biopsy. Treatment was reduction of immunosuppression and surveillance. The patient had a favorable evolution.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Trasplante de Riñón
/
Sirolimus
/
Inmunosupresores
/
Trastornos Linfoproliferativos
Tipo de estudio:
Factores de riesgo
Límite:
Niño
/
Femenino
/
Humanos
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2009
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Pontificia Universidad Católica de Chile/CL
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