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Seroprevalence of HBV, HCV and HIV co-infection in selected individuals from state of São Paulo, Brazil
Portelinha Filho, Alexandre Martins; Nascimento, Charles Ulloffo do; Tannouri, Talita Nicastro; Troiani, Charlene; Ascêncio, Eloah Lopes; Bonfim, Renata; D'Andrea, Lourdes Aparecida Zampieri; Prestes-Carneiro, Luiz Euribel.
  • Portelinha Filho, Alexandre Martins; Hospital Universitário. Departamento de Doenças Infecciosas. BR
  • Nascimento, Charles Ulloffo do; Hospital Universitário. Departamento de Doenças Infecciosas. BR
  • Tannouri, Talita Nicastro; Hospital Universitário. Departamento de Doenças Infecciosas. BR
  • Troiani, Charlene; Universidade do Oeste Paulista. Departamento de Imunologia. Presidente Prudente. BR
  • Ascêncio, Eloah Lopes; Universidade do Oeste Paulista. Departamento de Imunologia. Presidente Prudente. BR
  • Bonfim, Renata; Instituto Adolfo Lutz. Presidente Prudente. BR
  • D'Andrea, Lourdes Aparecida Zampieri; Instituto Adolfo Lutz. Presidente Prudente. BR
  • Prestes-Carneiro, Luiz Euribel; Universidade do Oeste Paulista. Departamento de Imunologia. Presidente Prudente. BR
Mem. Inst. Oswaldo Cruz ; 104(7): 960-963, Nov. 2009. tab, ilus
Artículo en Inglés | LILACS | ID: lil-534158
ABSTRACT
Few studies are available on hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) co-infection in populations living in small and medium-sized Brazilian cities. We evaluated the seroprevalence of these viruses in selected individuals from a clinic of infectology, who were referred to the University Regional Hospital of the West Region of state of São Paulo, Brazil. Among a total of 7,021 individuals seen in the clinic following receipt of preliminary ELISA results or having the suggested clinical signs of viral hepatitis or HIV, 1,228 were systematically screened. Isolated or associated HBsAg, HCV and HIV antibodies were found in 44.9 percent of the subjects. Anti-HIV antibodies were found in 24.7 percent of the patients, 20.3 percent of whom had an HIV monoinfection and 4.4 percent of whom were co-infected with hepatitis viruses (HCV 4 percent; HBV 0.4 percent). Anti-HCV antibodies were found in 14 percent of the patients and 5.9 percent had anti-HBsAg antibodies. HCV infection affected males more than females (p < 0.05) and individuals > 50-years old had an increased prevalence of anti-HCV compared to HIV (p = 0.0001) or HBV (p = 0.0063). HCV-RNA was detected in 73.5 percent of the samples with a predominance of genotype 1 (72.5 percent). A significant percentage (44.9 percent) of the selected individuals was positive for antibodies against HBV, HCV and/or HIV; these patients would otherwise have remained undiagnosed.
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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Seropositividad para VIH / Hepatitis C / Hepatitis B Tipo de estudio: Factores de riesgo Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: Mem. Inst. Oswaldo Cruz Asunto de la revista: Medicina Tropical / Parasitología Año: 2009 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Hospital Universitário/BR / Instituto Adolfo Lutz/BR / Universidade do Oeste Paulista/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Seropositividad para VIH / Hepatitis C / Hepatitis B Tipo de estudio: Factores de riesgo Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: Mem. Inst. Oswaldo Cruz Asunto de la revista: Medicina Tropical / Parasitología Año: 2009 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Hospital Universitário/BR / Instituto Adolfo Lutz/BR / Universidade do Oeste Paulista/BR