Fatal disseminated mucormycosis in a patient with mantle cell non-hodgkin's lymphoma: an autopsy case
Braz. j. infect. dis
;
13(3): 238-241, June 2009. ilus
Artículo
en Inglés
| LILACS
| ID: lil-538528
ABSTRACT
A patient with mantle cell non-Hodgkin's lymphoma presented herself with fever, nausea, right upper quadrant pain on the 7th day of R-CHOP chemotherapy. After hospitalization with the suspicion of acute cholecystitis, she received antibiotherapy with G-CSF because of emerging neutropenia at the 10th day of chemotherapy. Abdominal computed tomography revealed small infarcts in the spleen and kidneys. The echymotic lesion which developed on her right lateral malleolus, became bullous in the following days and treated as ecthyma gangrenosum. Altough the patient was afebrile with a normal neutrophil count on the third day of antibiotherapy, she developed acute renal failure and deteriorated rapidly. The patient underwent hemodialysis but expired on the 10th day of hospitalization. Post mortem autopsy findings showed ischemic infarction and necrosis of parenchyma due to mycotic thrombosis of arteries and veins of many organs (heart, lung, diaphgram, kidneys, spleen, gut mucosa) as well as invasion of vessel walls and parenchyma by mucor. We reviewed mucormycosis in the light of this case.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Linfoma de Células del Manto
/
Mucormicosis
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2009
Tipo del documento:
Artículo
País de afiliación:
Turquía
Institución/País de afiliación:
Dokuz Eylul University/TR
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