Actinic lesions in fishermen's lower lip: clinical, cytopathological and histopathologic analysis
Clinics
;
65(4): 363-367, 2010. tab
Artículo
en Inglés
| LILACS
| ID: lil-546310
ABSTRACT
INTRODUCTION:
Actinic cheilitis (AC) is considered to be a pre-malignant lesion or an incipient and superficial form of lip squamous cell carcinoma. It is commonly found in individuals whose occupational activities are related to chronic sun exposure and the definitive diagnosis is performed with biopsy. Althoug Exfoliative cytology has been used as a screening procedure to evaluate cancer of the oral cavity no studies have proposed the use of exfoliative cytologic analysis to evaluate and diagnose AC.OBJECTIVE:
The purpose of this study was to evaluate lower lip lesions on fishermen related to chronic solar exposure using clinical, cytologic and histopathologic analyses. PATIENTS ANDMETHODS:
Smears taken from the vermilion of the lower lips of 125 fishermen and 30 control individuals were subjected to cytologic analysis.RESULTS:
The harvested cells were sufficient for cytologic analysis in 83.2 percent of the samples. Sixteen fishermen exhibited prominent lower lip lesions that justified biopsy and histological studies. In total, 4 specimens were malignant (3.2 percent), and 12 displayed epithelial dysplasia, demonstrating that the prevalence of epithelial dysplasia and malignant lesions was high among the fishermen population. These conditions were strongly associated with infiltration and blurring of the vermilion margin of the lower lip.CONCLUSION:
The cytologic analysis was not useful for detecting epithelial dysplasia or malignant alterations.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Lesiones Precancerosas
/
Neoplasias de los Labios
/
Carcinoma de Células Escamosas
/
Queilitis
/
Labio
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Clinics
Asunto de la revista:
Medicina
Año:
2010
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de São Paulo/BR
/
Universidade do Sul de Santa Catarina/BR
/
University of São Paulo Dental School/BR
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