Hydroxylapatite implants with or without collagen in the zygomatic arch of rats: histological study

ABSTRACT

The authors studied the behaviour of calcium phosphate materials used as inlay implants into bone cavities prepared in the zygomatic arch of rats. Fifty male albino rats were divided into four groups as follows Group I - preparation of bone cavities which did not receive any implant material as controls; Group II - implants of Interpore© 200; Group III - implants of experimental hydroxylapatite; Group IV - implants of experimental hydroxilapatite combined whith collagen. The animals were sacrificed after 5, 15, 30, 60 and 120 days and specimens were submitted to histological analysis. Results showed that experimental hydroxylapatite used in group III presented better osteogenic properties compared to the other materials. All tested materials were biocompatible, although group IV presented a more intense inflammatory response.