High prevalence of drug-resistant tuberculosis and other mycobacteria among HIV-infected patients in Brazil: a systematic review
Mem. Inst. Oswaldo Cruz
;
105(6): 838-841, Sept. 2010. tab
Artículo
en Inglés
| LILACS, SES-SP
| ID: lil-560673
ABSTRACT
There is a little-noticed trend involving human immunodeficiency virus (HIV)-infected patients suspected of having tuberculosis the triple-treatment regimen recommended in Brazil for years has been potentially ineffective in over 30 percent of the cases. This proportion may be attributable to drug resistance (to at least 1 drug) and/or to infection with non-tuberculous mycobacteria. This evidence was not disclosed in official statistics, but arose from a systematic review of a few regional studies in which the diagnosis was reliably confirmed by mycobacterial culture. This paper clarifies that there has long been ample evidence for the potential benefits of a four-drug regimen for co-infected patients in Brazil and it reinforces the need for determining the species and drug susceptibility in all positive cultures from HIV-positive patients.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Infecciones Oportunistas Relacionadas con el SIDA
/
Tuberculosis Resistente a Múltiples Medicamentos
/
Infecciones por Mycobacterium no Tuberculosas
/
Antituberculosos
Tipo de estudio:
Estudio de prevalencia
/
Factores de riesgo
/
Revisiones Sistemáticas Evaluadas
Límite:
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Año:
2010
Tipo del documento:
Artículo
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