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Detecção de fibronectina e laminina em cistos teciduais de toxoplasma gondii: ensaios imunocitoquímicos / Detection of fibronectin and laminin in toxoplasma gondii tissue cysts: immunocytochemical assays
Guimarães, Erick Vaz; Acquarone, Mariana; Carvalho, Laís de; Barbosa, Helene Santos.
Afiliación
  • Guimarães, Erick Vaz; Instituto Oswaldo Cruz. Rio de Janeiro. BR
  • Acquarone, Mariana; Instituto Oswaldo Cruz. Rio de Janeiro. BR
  • Carvalho, Laís de; Universidade Federal do Rio de Janeiro. Rio de Janeiro. BR
  • Barbosa, Helene Santos; Instituto Oswaldo Cruz. Rio de Janeiro. BR
Sci. med ; 20(1)jan.-mar. 2010. ilus
Article en Pt | LILACS | ID: lil-567162
Biblioteca responsable: BR500.1
ABSTRACT

Aims:

To analyze the existence and distribution of some matrix proteins in tissue cysts of Toxoplasma gondii.

Methods:

Laminin and fibronectin in tissue cysts of Toxoplasma gondii were detected by confocal microscopy and transmission electron microscopy.

Results:

Ultrastructural immunocytochemistry showed both glycoproteins in the granular region of tissue cysts, cystic matrix, micronemes, rhoptries, dense granules and rarely at the membrane of bradyzoites of Toxoplasma gondii.

Conclusions:

The presence of both laminin and fibronectin in secretory organelles and in the apical region of bradyzoites suggests that exocytosis of these glycoproteins can contribute to their interaction with host cells, besides composing the cyst matrix of Toxoplasma gondii.
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Texto completo: 1 Índice: LILACS Asunto principal: Inmunohistoquímica / Glicoproteínas / Toxoplasmosis / Fibronectinas / Microscopía Electrónica de Transmisión / Microscopía Tipo de estudio: Diagnostic_studies Idioma: Pt Revista: Sci. med Año: 2010 Tipo del documento: Article
Texto completo: 1 Índice: LILACS Asunto principal: Inmunohistoquímica / Glicoproteínas / Toxoplasmosis / Fibronectinas / Microscopía Electrónica de Transmisión / Microscopía Tipo de estudio: Diagnostic_studies Idioma: Pt Revista: Sci. med Año: 2010 Tipo del documento: Article