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Comparison of 18FDG PET with thallium SPECT in the assessment of myocardial viability. A segmental model analysis
Alexánderson, Erick; Ricalde, Alejandro; Romero-Ibarra, José Luis; Meave, Aloha.
  • Alexánderson, Erick; Instituto Nacional de Cardiología lgnacio Chávez. MX
  • Ricalde, Alejandro; Universidad Nacional Autónoma de México. Medical School. MX
  • Romero-Ibarra, José Luis; Universidad Nacional Autónoma de México. Medical School. MX
  • Meave, Aloha; Instituto Nacional de Cardiología Ignacio Chávez. Department of Cardiovascular Magnetic Resonance. MX
Arch. cardiol. Méx ; 76(1): 9-15, ene.-mar. 2006.
Artículo en Inglés | LILACS | ID: lil-569532
ABSTRACT

BACKGROUND:

In patients with myocardial infarction and left ventricular dysfunction, the evidence of myocardial viability is primordial. There are some methods to detect the presence of myocardial viability, 201 thallium reinjection SPECT protocol represents the most common radioisotopic technique to evaluate it. Positron emission tomography (PET) using FDG is considered the gold standard. The aim of this study was to compare globally and by segments the value of both techniques in the detection of viable myocardium.

METHODS:

Twenty-three consecutive patients with previous myocardial infarction and left ventricular dysfunction were studied. All of them underwent into a SPECT perfusion scan and a FDG PET study to asses myocardial viability. Each study was performed in less than one week between the other. For the analysis, the myocardium was divided into 17 segments. A visual semi-quantitative analysis was carried out according to the following score indicating radiotracer uptake O = normal to 4 = absent. Myocardial viability was defined as the presence of normal, mildly or moderately reduced radiotracer uptake. The scores obtained by PET were compared to those obtained in SPECT. A statistical analysis was performed using the SPSS v. 10.

RESULTS:

391 segments were analyzed. PET detected viability in 130 segments that had been defined as non-viable by SPECT. No differences in the analysis by vascular territories were found. Thirty percent of the segments that were defined as non viable by SPECT were viable by PET, meanwhile only 1% of the segments detected viable by SPECT were considered non viable with PET.

CONCLUSIONS:

FDG PET study represents a better technique to detect myocardial viability, compared to thallium reinjection SPECT protocol. By this study we have demonstrated that more of 3 of each 10 studies may be diagnosed as non viable where viability is present.
Asunto(s)
Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Radioisótopos de Talio / Tomografía Computarizada de Emisión de Fotón Único / Radiofármacos / Tomografía de Emisión de Positrones / Infarto del Miocardio Tipo de estudio: Guía de Práctica Clínica / Estudio pronóstico Límite: Femenino / Humanos / Masculino Idioma: Inglés Revista: Arch. cardiol. Méx Asunto de la revista: Cardiología Año: 2006 Tipo del documento: Artículo País de afiliación: México Institución/País de afiliación: Instituto Nacional de Cardiología Ignacio Chávez/MX / Instituto Nacional de Cardiología lgnacio Chávez/MX / Universidad Nacional Autónoma de México/MX

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Radioisótopos de Talio / Tomografía Computarizada de Emisión de Fotón Único / Radiofármacos / Tomografía de Emisión de Positrones / Infarto del Miocardio Tipo de estudio: Guía de Práctica Clínica / Estudio pronóstico Límite: Femenino / Humanos / Masculino Idioma: Inglés Revista: Arch. cardiol. Méx Asunto de la revista: Cardiología Año: 2006 Tipo del documento: Artículo País de afiliación: México Institución/País de afiliación: Instituto Nacional de Cardiología Ignacio Chávez/MX / Instituto Nacional de Cardiología lgnacio Chávez/MX / Universidad Nacional Autónoma de México/MX