Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
Arq. bras. med. vet. zootec
;
62(6): 1495-1498, dez. 2010. ilus
Artículo
en Portugués
| LILACS
| ID: lil-576052
ABSTRACT
Samples from intestines, liver, and lymph nodes were collected from a dairy steer with clinical suspicion of paratuberculosis. The samples were processed for histologic examination with hematoxylin-eosin and Zihel-Neelsen (ZN) staining for the detection of acid-fast bacilli (AFB), and submitted to immunohistochemistry (IHC). Macroscopic changes were observed in the small intestines, with thickening and corrugation of the mucosa. The main microscopic changes were found in small intestines, lymph vessels in the mesentery, and mesenteric lymph nodes characterized by enteritis, lymphangiectasia, and lymphadenitis. Liver presented with granulomatous hepatitis, an uncommon histopathological feature for paratuberculosis. The clinical features associated with positive culture of Mycobacterium avium subsp. paratuberculosis and detection of AFB by ZN and IHC in the cytoplasm of macrophages (epithelioid) in the intestinal mucosa and submucosa, lymph nodes, and liver were important to confirm the diagnosis of paratuberculosis.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Hepatitis
/
Mycobacterium
Límite:
Animales
Idioma:
Portugués
Revista:
Arq. bras. med. vet. zootec
Asunto de la revista:
Medicina Veterinaria
Año:
2010
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fundação Oswaldo Cruz/BR
/
Instituto Federal de Educação do Pará/BR
/
Universidade Estadual do Norte Fluminense Darcy Ribeiro/BR
/
Universidade Federal Fluminense/BR
/
Universidade Federal do Rio de Janeiro/BR
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