Clinical and microbiological characterization of KPC-producing Klebsiella pneumoniae infections in Brazil
Braz. j. infect. dis
;
15(1): 69-73, Jan.-Feb. 2011. tab
Artículo
en Inglés
| LILACS
| ID: lil-576789
ABSTRACT
In 2008 isolates of KPC-producing Klebsiella pneumoniae (KPC-KPN) were detected for the first time at Hospital Heliópolis, São Paulo, Brazil. The aim of this study was to characterize the clinical and microbiological outcomes of infections caused by KPC-KPN. A historical cohort of patients from whom KPC-KPN strains were isolated was performed. Isolates were identified as resistant to ertapenem by automated broth microdilution system and screened as carbapenemase producers by the modified Hodge test. The beta-lactamase resistance gene blaKPC was detected by PCR. The genetic relatedness of isolates was determined by PFGE. The study provides early clinical experience in treating KPC-KPN infections in a Brazilian tertiary center.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Proteínas Bacterianas
/
Beta-Lactamasas
/
Infecciones por Klebsiella
/
Klebsiella pneumoniae
/
Antibacterianos
Tipo de estudio:
Estudio pronóstico
Límite:
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2011
Tipo del documento:
Artículo
País de afiliación:
Brasil
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