Acute effect of phosphodiesterase type 5 inhibitor on serum oxidative status and prolidase activities in men with erectile dysfunction
Clinics
;
65(12): 1311-1314, 2010. tab
Artículo
en Inglés
| LILACS
| ID: lil-578570
ABSTRACT
OBJECTIVES:
To investigate the acute effect of phosphodiesterase type 5 (PDE5) inhibitor on erectile dysfunction by evaluating serum oxidative status and prolidase activity.METHODS:
Serum samples of 36 patients with erectile dysfunction and 30 control cases were analyzed for total antioxidant status, total oxidant status, and prolidase activity, before and after the administration of tadalafil citrate.RESULTS:
Before and after tadalafil citrate administration, serum total antioxidant status, total oxidant status, and prolidase were 1.1+0.0 vs. 1.6 + 0.0 umol H2O2 Eq/L, 10.3+1.1 vs. 6.9 + 1.2 umol H2O2 Eq/L, and 236.4+19.5 vs. 228.2 + 19.2 U/L, respectively (p<0.0001 for all).CONCLUSIONS:
Evaluation of serum oxidative status and prolidase activity confirmed the beneficial acute effects of PDE5 inhibitor in patients with erectile dysfunction.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Carbolinas
/
Estrés Oxidativo
/
Dipeptidasas
/
Disfunción Eréctil
Tipo de estudio:
Estudio observacional
Límite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Clinics
Asunto de la revista:
Medicina
Año:
2010
Tipo del documento:
Artículo
País de afiliación:
Turquía
Institución/País de afiliación:
Harran University/TR
/
Sanliurfa Research Hospital/TR
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