Platelet-rich plasma plus bioactive glass in the treatment of intra-bony defects: a study in dogs
J. appl. oral sci
;
19(1): 82-89, Jan.-Feb. 2011. ilus, graf, tab
Artículo
en Inglés
| LILACS
| ID: lil-578753
ABSTRACT
OBJECTIVE:
This study was designed to evaluate, histomorphometrically, the association of platelet-rich plasma (PRP) and bioactive glass (BG) in the treatment of periodontal intrabony defects. MATERIAL ANDMETHODS:
Nine mongrel dogs were included in the study. Three-wall intrabony defects were surgically created at the mesial and distal aspect of first mandibular molar and exposed to plaque accumulation for 1 month. The defects were randomly assigned to the groups control, BG, PRP, PRP+BG. Dogs were sacrificed 90 days after the surgeries. The histometric parameters evaluated were length of sulcular and junctional epithelium, connective tissue adaptation, new cementum, new bone, defect extension and area of new bone filling the defect.RESULTS:
A superior area of new bone was observed in PRP+BG and BG (13.80±2.32 mm² and 15.63±2.64 mm², respectively) when compared to the other groups (8.19±1.46 mm² and 8.81±1.47 mm² for control and PRP, respectively). No statistically significant differences were observed in the remaining parameters.CONCLUSIONS:
Within the limits of this study, it may be concluded that PRP failed to provide statistically significant improvements in the histometric parameters.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Regeneración Ósea
/
Cerámica
/
Sustitutos de Huesos
/
Plasma Rico en Plaquetas
Límite:
Animales
Idioma:
Inglés
Revista:
J. appl. oral sci
Asunto de la revista:
Odontología
Año:
2011
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Brasil
Institución/País de afiliación:
State University of Amazonas/BR
/
University of Campinas/BR
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