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Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
Ferraz, Helena O; Silva, Magali G; Carvalho, Rui; Suffredini, Ivana B; Kato, Edna T. M; Arakaki, Fernanda; Bacchi, Elfriede M.
  • Ferraz, Helena O; University of Sorocaba. Sorocaba. BR
  • Silva, Magali G; University of Sorocaba. Sorocaba. BR
  • Carvalho, Rui; College of Sciences and Technology of University of Coimbra. Department of Biochemistry. Coimbra. PT
  • Suffredini, Ivana B; Paulista University. Laboratory of Extraction. São Paulo. BR
  • Kato, Edna T. M; University of São Paulo. College of Pharmaceutical Sciences. Department of Pharmacy. São Paulo. BR
  • Arakaki, Fernanda; University of São Paulo. College of Pharmaceutical Sciences. Department of Pharmacy. São Paulo. BR
  • Bacchi, Elfriede M; University of São Paulo. College of Pharmaceutical Sciences. Department of Pharmacy. São Paulo. BR
Rev. bras. farmacogn ; 21(1): 41-46, jan.-fev. 2011. ilus, tab
Artículo en Inglés | LILACS | ID: lil-580332
ABSTRACT
Cuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79 percent and 2.01 percent, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100 percent of the brine shrimp used for the test.


Texto completo: Disponible Índice: LILACS (Américas) Idioma: Inglés Revista: Rev. bras. farmacogn Asunto de la revista: Farmacia Año: 2011 Tipo del documento: Artículo País de afiliación: Brasil / Portugal Institución/País de afiliación: College of Sciences and Technology of University of Coimbra/PT / Paulista University/BR / University of Sorocaba/BR / University of São Paulo/BR

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Texto completo: Disponible Índice: LILACS (Américas) Idioma: Inglés Revista: Rev. bras. farmacogn Asunto de la revista: Farmacia Año: 2011 Tipo del documento: Artículo País de afiliación: Brasil / Portugal Institución/País de afiliación: College of Sciences and Technology of University of Coimbra/PT / Paulista University/BR / University of Sorocaba/BR / University of São Paulo/BR