Risk factors for oral candidiasis in Brazilian HIV-infected adult patients
Braz. j. oral sci
;
9(4): 470-474, Oct.-Dec. 2010. tab
Artículo
en Inglés
| LILACS, BBO
| ID: lil-582280
ABSTRACT
Aim:
The goals of this study were 1) to estimate the prevalence of oral candidiasis (OC) in a sample of Brazilian HIV-infected adult patients, and 2) to investigate the risk factors for HIVassociated OC in this sample.Methods:
This case-control study included 112 HIV-infected patients treated between 2002 and 2004 at a clinic for sexually transmitted diseases. Data were collected from medical records and clinical examinations. Diagnosis of OC was performed in accordance with the International Classification System and cytological features. Seventeen clinical and laboratorial variables were registered. Univariate analyses were performed on all variables. Multiple logistic regression techniques were used to develop a model and identify the set of variables that may predict risk factors in HIV-infected adult patients with OC.Results:
Prevalence of OC was 31.3%. OC was associated with oral hairy leukoplakia (OHL) [p<0.001; odds ratio (OR) = 10.2 (95%CI 4.0-26.0)], previous use of fluconazole [p<0.001; OR=27.4 (95%CI 8.1-92.0)] and viral load [p=0.042; OR=2.3 (95%CI 1.0-5.3)].Conclusions:
These results are important for the development of strategies to eliminate these risk factors and significantly reduce OC in HIV-infected patients.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Candidiasis Bucal
/
Infecciones por VIH
/
Terapia Antirretroviral Altamente Activa
/
Antifúngicos
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Braz. j. oral sci
Asunto de la revista:
Odontología
Año:
2010
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Brasil
Institución/País de afiliación:
Faculdades Pitágoras/BR
/
Federal University of Minas Gerais/BR
/
Federal University of Vales Jequitinhonha and Mucuri/BR
Similares
MEDLINE
...
LILACS
LIS