Brazilian Guidelines for transcranial doppler in children and adolescents with sickle cell disease
Rev. bras. hematol. hemoter
;
33(1): 43-48, Feb. 2011. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-582747
ABSTRACT
BACKGROUND:
Sickle cell disease is the most common monogenic hereditary disease in Brazil. Although strokes are one of the main causes of morbidity and mortality in these patients, the use of transcranial Doppler to identify children at risk is not universally used.OBJECTIVE:
To develop Brazilian guidelines for the use of transcranial Doppler in sickle cell disease children and adolescents, so that related health policies can be expanded, and thus contribute to reduce morbidity and mortality.METHODS:
The guidelines were formulated in a consensus meeting of experts in transcranial Doppler and sickle cell disease. The issues discussed were previously formulated and scientific articles in databases (MEDLINE, SciELO and Cochrane) were carefully analyzed. The consensus for each question was obtained by a vote of experts on the specific theme.RESULTS:
Recommendations were made, including indications for the use of transcranial Doppler according to the sickle cell disease genotype and patients age; the necessary conditions to perform the exam and its periodicity depending on exam results; the criteria for the indication of blood transfusions and iron chelation therapy; the indication of hydroxyurea; and the therapeutic approach in cases of conditional transcranial Doppler.CONCLUSION:
The Brazilian guidelines on the use of transcranial doppler in sickle cell disease patients may reduce the risk of strokes, and thus reduce the morbidity and mortality and improve the quality of life of sickle cell disease patients.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Hemoglobina Falciforme
/
Niño
/
Adolescente
/
Guía
/
Ultrasonografía Doppler Transcraneal
/
Accidente Cerebrovascular
/
Anemia de Células Falciformes
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio pronóstico
Límite:
Adolescente
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
/
Lactante
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. bras. hematol. hemoter
Asunto de la revista:
Hematología
Año:
2011
Tipo del documento:
Artículo
País de afiliación:
Brasil
/
Estados Unidos
Institución/País de afiliación:
Ecodopler Laboratório/BR
/
Faculdade de Ciências Médicas da Santa Casa de São Paulo/BR
/
Fundação Centro de Hematologia e Hemoterapia de Minas Gerais/BR
/
Fundação Hemocentro/BR
/
Fundação de Hematologia e Hemoterapia de Pernambuco/BR
/
Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti/BR
/
Medical University of South Carolina/US
/
UFRGS/BR
/
Universidade Federal de São Paulo/BR
/
Universidade Federal do Paraná/BR
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