Avaliação do efeito de mikania glomerata sobre o sistema reprodutor e órgaõs de ratos wistar submetidos a tratamento subagudo / Short-term exposure to mikania glomerata on male wistar rats' organs and reproductive system
Bol. Centro Biol. Reprod
;
23: 39-49, 2004.
Artículo
en Portugués
| LILACS
| ID: lil-586306
ABSTRACT
Mikania glomerata (guaco) is a plant well known in Brazil for its therapeutic properties, especially in the treatament of respiratory diseases. Coumarin and flavonoids are active compounds of M. glomerata leaves and have been reported to cause adverse effects on the organism, including antifertility activity in famale rat and male dog respectively. This work analyzes the effect of short-term administration of M.glomerata hydroalcoholic extract on vital organs, of the reproductive system and sperm concentration of mature male wistar rats. Treated animals received 1 ml of the extract at a dose of 1.1 g/kg of body weight for live days. Body and organs weights, sperm production and food consumption were evaluated. No body weigth reduction and no toxic effect on the organs, gamete production or food intake were detected in any of the groups analyzed, given the experimental protocol used.
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Índice:
LILACS (Américas)
Asunto principal:
Ratas Wistar
/
Mikania
Tipo de estudio:
Estudios de evaluación
/
Guía de Práctica Clínica
Límite:
Animales
Idioma:
Portugués
Revista:
Bol. Centro Biol. Reprod
Asunto de la revista:
REPRODUCAO
Año:
2004
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal da Paraíba/BR
/
Universidade Federal de Juiz de Fora/BR
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