A rapid detection of multidrug-resistant Mycobacterium tuberculosis by a nitrate reductase assay on blood agar
Mem. Inst. Oswaldo Cruz
;
106(3): 378-380, May 2011. tab
Artículo
en Inglés
| LILACS
| ID: lil-589052
ABSTRACT
The susceptibility of 49 Mycobacterium tuberculosis clinical isolates to isoniazid (INH) and rifampisin (RIF) (28 multi-drug resistant-tuberculosis samples) was determined by a nitrate reductase assay (NRA) on blood agar. Agreement between the NRA and other testing methods was found to be 93.8 percent for both INH and RIF. The sensitivity, specificity, positive predictive value and negative predictive value for INH were 92.8 percent, 94.2 percent, 86.6 percent and 97 percent, respectively. The sensitivity, specificity, positive predictive value and negative predictive value for RIF were 90.4 percent, 96.4 percent, 95 percent and 93.1 percent. In conclusion, we show here that blood agar can be used effectively for the NRA test.
Texto completo:
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Índice:
LILACS (Américas)
Asunto principal:
Rifampin
/
Farmacorresistencia Bacteriana Múltiple
/
Isoniazida
/
Mycobacterium tuberculosis
/
Antituberculosos
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2011
Tipo del documento:
Artículo
País de afiliación:
Turquía
Institución/País de afiliación:
Istanbul University/TR
/
Ondokuz Mayis University/TR
/
Samsun Chest Diseases Hospital/TR
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