Polyoma BK virus: an emerging opportunistic infectious agent of the human central nervous system
Braz. j. infect. dis
;
15(3): 276-284, May-June 2011. tab
Artículo
en Inglés
| LILACS
| ID: lil-589962
ABSTRACT
BK virus, a double-stranded DNA virus, is a member of the Polyomaviridae family which is known to infect humans. Clinical evidence of disease is mostly encountered in immunosuppressed individuals such as AIDS patients or those who undergo renal or bone marrow transplantation where complications associated with BKV infection manifest commonly as a polyomavirus nephropathy or hemorrhagic cystitis, respectively. Recent evidence suggests that in addition to the JC virus (the other member of the same family known to be strongly neurotropic and responsible for the progressive multifocal leukoencephalopathy), BK virus can infect and cause clinically relevant disease in the human central nervous system. In this mini-review, an analysis of the literature is made. A special focus is given to alert clinicians to the possibility of this association during the differential diagnosis of infections of the central nervous system in the immunocompromised host.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Infecciones Tumorales por Virus
/
Infecciones Oportunistas
/
Infecciones del Sistema Nervioso Central
/
Virus BK
/
Enfermedades Transmisibles Emergentes
/
Infecciones por Polyomavirus
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2011
Tipo del documento:
Artículo
País de afiliación:
Portugal
Institución/País de afiliación:
CHLC/PT
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