Characterization of a gelatin/chitosan/hyaluronan scaffold-polymer
Electron. j. biotechnol
;
13(5): 20-21, Sept. 2010. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-591902
ABSTRACT
Gelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prepared and characterized a Gelatin/Chitosan/Hyaluronan lyophilized-polymer. Physical properties of lyophilized-polymer changed slightly with moisture, but when polymer was totally hydrated the elasticity changed significantly. Thermophysical characterisation indicated that temperatures higher than 30ºC could modify irreversibly the polymeric matrix probably due to protein denaturation. Besides, we used the polymer as scaffold to prepare a biosynthetic-skin, reporting biological behaviour and its mechanical properties.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Quitosano
/
Gelatina
/
Ácido Hialurónico
Idioma:
Inglés
Revista:
Electron. j. biotechnol
Asunto de la revista:
Biotecnologia
Año:
2010
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Chile
Institución/País de afiliación:
Universidad Técnica Federico Santa María/CL
/
Universidad de Santiago de Chile/CL
/
Universidad de Valparaíso/CL
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