Association between anemia and subclinical infection in children in Paraíba State, Brazil
Rev. bras. hematol. hemoter
;
33(2): 96-99, 2011. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-596296
ABSTRACT
BACKGROUND:
With subclinical infection, serum iron concentrations are reduced, altering the synthesis of hemoglobin, the main indicator of anemia.OBJECTIVE:
To evaluate the association between subclinical infection and anemia in children of Paraíba State.METHODS:
This is a cross-sectional study involving 1116 children aged 6 to 59 months from nine municipalities of Paraíba State. Demographic and socioeconomic data were collected by means of a specific questionnaire. The C-reactive protein and hemoglobin levels were determined by the latex agglutination technique and automated counter, respectively. C-reactive protein values > 6 mg/L were used as indicative of subclinical infection, while the presence of anemia was determined by hemoglobin values < 11.0 g/dL. The data were analyzed using the Epi Info computer program, with significance being set at 5 percent.RESULTS:
Data from this research showed that 80.1 percent of the children belonged to families that were below the bread line, with per capita income < ½ of the minimum wage at that time (R$ 350.00 approximately US$ 175.00). The prevalences of subclinical infection and anemia were 11.3 percent and 36.3 percent, respectively. Subclinical infection was significantly associated with anemia (p-value < 0.05). There were lower levels of hemoglobin in children with C-reactive protein > 6 mg/L, with a mean hemoglobin level in children with subclinical infection of 10.93 g/dL (standard deviation - SD = 1.21 g/dL) and without infection of 11.26 g/dL (SD = 1.18 g/dL) (p-value < 0.05).CONCLUSION:
Anemia is associated with subclinical infection in this population, indicating that this is an important variable to be considered in studies of the prevalence of anemia in children.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Hemoglobinas
/
Niño
/
Salud Pública
/
Infecciones
/
Anemia
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Child, preschool
/
Femenino
/
Humanos
/
Lactante
/
Masculino
/
Recién Nacido
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. bras. hematol. hemoter
Asunto de la revista:
Hematología
Año:
2011
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Estadual da Paraíba/BR
/
Universidade Federal da Paraíba/BR
/
Universidade Federal do Piauí/BR
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