Inflammatory edema induced by carrageenin in monosodium glutamate-treated rats
Braz. j. med. biol. res
;
21(4): 837-9, 1988. ilus
Artículo
en Inglés
| LILACS
| ID: lil-60802
RESUMO
Rats treated with monosodium glutamate (MSG) during the neonatal period show hypothalamic lesions and multiple neuroendocrine alterations manifested as a remarkable increase in levels of circulating corticosterone and obesity. Paw edema induced by local injection of carrageenin was significantly reduced in MSG-treated rats compared to normal rats. In contrast, both adrenalectomized rats and adrenalectomized, MSG-treated rats showed an increased response to carrageenin relative to controls. These results suggest that glucocorticoids are important modulators of inflammation in this phase of the process
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Índice:
LILACS (Américas)
Asunto principal:
Glutamato de Sodio
/
Carragenina
/
Edema
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1988
Tipo del documento:
Artículo
/
Congreso y conferencia
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