Evidence of an association between the O blood group and allergic rhinitis
Rev. bras. hematol. hemoter
;
33(6): 444-448, Dec. 2011. tab
Artículo
en Inglés
| LILACS
| ID: lil-611381
ABSTRACT
OBJECTIVE:
The aim of this study was to verify if ABO phenotypes are associated with allergic rhinitis.METHODS:
168 patients with allergic rhinitis and 168 control individuals from the same geographical region and paired by gender and age were enrolled in the study. ABO phenotypes were identified in red blood cells using the hemagglutination technique. The Fisher exact and chi-squared tests were employed to compare proportions. Statistical significance was set for an alpha error of 5 percent (p-value < 0.05).RESULTS:
The overall differences in the frequencies of the ABO phenotypes of patients and controls were marginal (χ2 7.569; degrees of freedom (DF) 3; p-value = 0.055) however the O blood group was associated with allergic rhinitis (χ2 5.764; DF 1; p-value = 0.016; OR 1.735; CI 95 percent 1.127-2.673). The differences in the frequencies of the O phenotype in patients and controls were statistically different for men (χ2 8.520; DF 1; p-value = 0.003) but not for women (χ2 0.6375; DF 1; p-value = 0.4246). The A phenotype was associated with protection (OR 0.4385; CI 95 percent 0.2043-0.9415; p-value = 0.049) and the O phenotype was associated with susceptibility (OR = 2.789; CI 95 percent 1.385-5.616; p-value = 0.005) to allergic rhinitis only for men.CONCLUSION:
The O blood group phenotype is associated with allergic rhinitis in male but not in female patients.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Hipersensibilidad Respiratoria
/
Asma
/
Sistema del Grupo Sanguíneo ABO
/
Rinitis Alérgica Estacional
/
Hipersensibilidad
Tipo de estudio:
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
Idioma:
Inglés
Revista:
Rev. bras. hematol. hemoter
Asunto de la revista:
Hematología
Año:
2011
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Faculdade de Medicina de São José do Rio Preto/BR
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