Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
Rev. bras. farmacogn
;
22(2): 374-380, Mar.-Apr. 2012. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-624662
ABSTRACT
Conchocarpus fontanesianus (A. St.-Hill.) Kallunki & Pirani, Rutaceae, popularly known as pitaguará, is a native and endemic tree from São Paulo and Rio de Janeiro States, Brazil. Based in the information that anticholinesterasic derivatives could act as new prototypes to treatment of Alzheimer disease, this work describes the fractionation guided by evaluation of the anticholinesterase activity of the ethanolic stems extract from C. fontanesianus. This procedure afforded the alkaloids dictamnine (1), γ-fagarine (2), skimianine (3), and 2-phenyl-1-methyl-4-quinolone (4), as well as the coumarin marmesin (5).
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Índice:
LILACS (Américas)
Idioma:
Inglés
Revista:
Rev. bras. farmacogn
Asunto de la revista:
Farmacia
Año:
2012
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Instituto de Botânica de São Paulo/BR
/
Universidade Estadual de Campinas/BR
/
Universidade Federal de São Paulo/BR
/
Universidade de São Paulo/BR
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