Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional / Plasma fructosamine to evaluate metabolic control among women with gestational diabetes
Rev. méd. Chile
;
139(11): 1444-1450, nov. 2011. ilus
Artículo
en Español
| LILACS
| ID: lil-627574
ABSTRACT
Background: Metabolic control of diabetic pregnant women is assessed using glycated hemoglobin (HbAlc) levels and fasting blood sugar. Another glycated protein, namely fructosamine, can be an indicator of average glucose levels during the last three weeks. Aim: To evaluate plasma fructosamine as an indicator of glycemic control in women with gestational diabetes. Patients and Methods: Prospective cohort study of 41 pregnant women aged 30 to 37 years, with gestational and pre-gestational diabetes. Blood glucose, HbAlc, fructosamine were measured. Newborn weight, and other prenatal and postnatal variables, were used to evaluate the correlation between metabolic control and the presence or absence of macrosomia. Results: The correlation observed between fructosamine and fasting blood glucose (r = 0.627, p < 0.001) was superior to that of HbA1c and blood glucose (r = 0.516, p < 0.001). No association was observed between macrosomia and levels of fructosamine, nor between the other studied variables. Conclusions: Fructosamine levels were not associated with macrosomia, but it could be better for the evaluation of glycemic control in patients with gestational diabetes since it allows short-term monitoring.
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Índice:
LILACS (Américas)
Asunto principal:
Glucemia
/
Macrosomía Fetal
/
Hemoglobina Glucada
/
Ayuno
/
Diabetes Gestacional
/
Fructosamina
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Embarazo
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2011
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Hospital Barros Luco Trudeau/CL
/
Hospital Eduardo Pereira/CL
/
Hospital de Mejillones/CL
/
Universidad de Valparaíso/CL
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