Disfunción cognitiva después de cirugía cardiaca: Saturación cerebral e índice biespectral: estudio longitudinal / Neuropsychological dysfunction after cardiac surgery: Cerebral saturation and bispectral index: A longitudinal study
Rev. méd. Chile
;
139(12): 1553-1561, dic. 2011. ilus, tab
Artículo
en Español
| LILACS
| ID: lil-627589
ABSTRACT
Background:
Neuropsychological dysfunction is a major cause of morbidity and mortality after cardiac surgery.Aim:
To evaluate if intraoperative cerebral desatu-ration and depth of anesthesia measured by bispectral index are related to postoperative cognitive dysfunction in cardiac surgery. Material andMethods:
Prospective study in patients undergoing elective cardiac surgery with cardiopulmonary bypass. A comprehensive neuropsychological assessment was applied preoperatively and 3 months after surgery. Postoperative dysfunction was defined as a decrease of at least one standard deviation in two or more neuropsychological tests. Cerebral oxygenation and bispectral index were continuously recorded and corrected throughout surgery. Cerebral oxygenation data were analyzed by the mean value and at three thresholds 50%, 40% and < 25% of the basal value. Bispectral index was analyzed at threshold of 45.Results:
Fifty-six patients were initially enrolled and 48 completed the study. Nine of these (18.8 %) presented postoperative cognitive dysfunction. Mean cerebral saturation and bispectral index data were not different among the patients with or without cognitive dysfunction. There was no association between cerebral desaturation and bispectral index with changes in neurocognitive tests or with length of stay in the intensive care unit. A significant but weak correlation was found between baseline Ray-neurocognitive score and intensive care unit stay (rho = -0.46; P = 0.001).Conclusions:
We did not find a significant association between cerebral desaturation and depth of anesthesia with postoperative cognitive decline in this population of patients.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Consumo de Oxígeno
/
Circulación Cerebrovascular
/
Puente de Arteria Coronaria
/
Monitoreo Intraoperatorio
/
Trastornos del Conocimiento
/
Anestesia
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio observacional
/
Factores de riesgo
Límite:
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2011
Tipo del documento:
Artículo
País de afiliación:
Chile
/
España
Institución/País de afiliación:
Fundación Clínic/ES
/
Hospital Clínic/ES
/
Hospital Clínico Universidad de Chile/CL
/
Hospital Universitario Mar-IMAS/ES
Similares
MEDLINE
...
LILACS
LIS