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Candidemia in a brazilian tertiary hospital: microbiological and clinical features over a six-year period
Mondelli, A. L; Niéro-Melo, L; Bagagli, E; Camargo, C. H; Bruder-Nascimento, A; Sugizaki, M. F; Carneiro, M. V; Villas Boas, P. J. F.
  • Mondelli, A. L; São Paulo State University. Botucatu Medical School. Department of Internal Medicine. Botucatu. BR
  • Niéro-Melo, L; São Paulo State University. Botucatu Medical School. Department of Internal Medicine. Botucatu. BR
  • Bagagli, E; São Paulo State University. Botucatu Biosciences Institute. Department of Microbiology and Immunology. Botucatu. BR
  • Camargo, C. H; São Paulo State University. Botucatu Biosciences Institute. Department of Microbiology and Immunology. Botucatu. BR
  • Bruder-Nascimento, A; São Paulo State University. Botucatu Biosciences Institute. Department of Microbiology and Immunology. Botucatu. BR
  • Sugizaki, M. F; São Paulo State University. Botucatu Biosciences Institute. Department of Microbiology and Immunology. Botucatu. BR
  • Carneiro, M. V; São Paulo State University. Botucatu Medical School. Department of Internal Medicine. Botucatu. BR
  • Villas Boas, P. J. F; São Paulo State University. Botucatu Medical School. Department of Internal Medicine. Botucatu. BR
J. venom. anim. toxins incl. trop. dis ; 18(2): 244-252, 2012. graf, tab
Artículo en Inglés | LILACS, VETINDEX | ID: lil-639484
ABSTRACT
Yeasts are becoming a common cause of nosocomial fungal infections in immunocompromised patients. Such infections often develop into sepsis with high mortality rates. The aim of this study was to evaluate some of the numerous factors associated with the development of candidemia. Medical records were retrospectively analyzed of 98 Candida spp. patients. Results showed that the most prevalent risk factors for developing candidemia were antibiotics and antifungal agents (93.9% and 79.6%, respectively); the use of central venous catheter (93.9%); mechanical ventilation (73.5%); and parenteral nutrition (60.2%). The main species of Candida found were C. parapsilosis (37.76%), C. albicans (33.67%); and others (28.57%). C. glabrata showed the highest mortality rate (75%), followed by C. tropicalis (57.1%) and C. albicans (54.5%). The elevated mortality rate found in this study indicates that preventive measures against candidemia must be emphasized in hospitals.(AU)
Asunto(s)


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Candida / Factores de Riesgo / Candidemia / Micosis Tipo de estudio: Estudio de etiología / Factores de riesgo País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: J. venom. anim. toxins incl. trop. dis Año: 2012 Tipo del documento: Artículo Institución/País de afiliación: São Paulo State University/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Candida / Factores de Riesgo / Candidemia / Micosis Tipo de estudio: Estudio de etiología / Factores de riesgo País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: J. venom. anim. toxins incl. trop. dis Año: 2012 Tipo del documento: Artículo Institución/País de afiliación: São Paulo State University/BR