Motivation and frustration in cardiology trial participation: the patient perspective
Clinics
;
67(6): 603-608, 2012. tab
Artículo
en Inglés
| LILACS
| ID: lil-640210
ABSTRACT
OBJECTIVE:
The participation of humans in clinical cardiology trials remains essential, but little is known regarding participant perceptions of such studies. We examined the factors that motivated participation in such studies, as well as those that led to participant frustration.METHODS:
Patients who had participated in hypertension and coronary arterial disease (phases II, III, and IV) clinical trials were invited to answer a questionnaire. They were divided into two groups Group I, which included participants in placebo-controlled clinical trials after randomization, and Group II, which included participants in clinical trials in which the tested treatment was compared to another drug after randomization and in which a placebo was used in the washout period.RESULTS:
Eighty patients (47 patients in Group I and 33 patients in Group II) with different socio-demographic characteristics were interviewed. Approximately 60% of the patients were motivated to participate in the trial with the expectation of personal benefit. Nine participants (11.2%) expressed the desire to withdraw, which was due to their perception of risk during the testing in the clinical trial (Group I) and to the necessity of repeated returns to the institution (Group II). However, the patients did not withdraw due to fear of termination of hospital treatment.CONCLUSIONS:
Although this study had a small patient sample, the possibility of receiving a benefit from the new tested treatment was consistently reported as a motivation to participate in the trials.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Participación del Paciente
/
Cardiología
/
Ensayos Clínicos Controlados Aleatorios como Asunto
/
Investigación Biomédica
/
Frustación
/
Motivación
Tipo de estudio:
Ensayo Clínico Controlado
/
Investigación cualitativa
Límite:
Adulto
/
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Clinics
Asunto de la revista:
Medicina
Año:
2012
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de São Paulo/BR
/
University Estadual Paulista/BR
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