Low protein diet during perinatal period decreasesthe number of subepicardial neurons in rats
Braz. j. morphol. sci
;
26(3/4): 181-185, July-Dec. 2009. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-644176
ABSTRACT
Subepicardial plexus of the atria is an interdependent heart control system and its structure and functionmay be influenced by external factors. We studied the influence of protein deprivation on subepicardialneurons at early development stages by subjecting rats to a low protein diet (5% of casein) during pre and postnatal period. Atrial neurons were identified by histochemical methods b-nicotinamide adenine dinucleotide(NADH) reaction, b-nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) reaction andAcetylcholinesterase (AChE) reaction and counted in 21 day-old rats. Besides a significant reduction in bodyand heart weight, the total number of neurons decreased 46% in the undernourished group as compared tocontrol animals. Our data suggest that deficient nutrition during early developmental period may produceirreversible deleterious changes later in life.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Proteínas
/
Desarrollo Embrionario
/
Neuronas
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
/
Embarazo
Idioma:
Inglés
Revista:
Braz. j. morphol. sci
Asunto de la revista:
Anatomía
Año:
2009
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
São Judas Tadeu University/BR
/
University of São Paulo/BR
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