Comparative analysis of the intracerebral mouse protection test and serological method for potency assays of pertussis component in DTP vaccine
Braz. j. microbiol
;
43(2): 429-431, Apr.-June 2012. graf, tab
Artículo
en Inglés
| LILACS
| ID: lil-644455
ABSTRACT
The aim of this study was to compare the PSPT standardized in-house as an alternative to MPT for potency assays of pertussis component. Statistical analyses have showed similar pertussis potency values when PSPT was compared to MPT. Significant correlation between the potency results obtained by in vivo and in vitro assays was also been observed. Results by PSPT have demonstrated reproducibility and accuracy for potency pertussis control and this approach has been considered promising for use at least during the steps of production.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Bordetella pertussis
/
Tos Ferina
/
Técnica de Inmunoensayo de Enzimas Multiplicadas
/
Técnicas y Procedimientos Diagnósticos
Tipo de estudio:
Estudio diagnóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. microbiol
Asunto de la revista:
Microbiologia
Año:
2012
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fundação Instituto Oswaldo Cruz/BR
/
Instituto Butantan/BR
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