Protein turnover, amino acid requirements and recommendations for athletes and active populations
Braz. j. med. biol. res
;
45(10): 875-890, Oct. 2012. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-647756
ABSTRACT
Skeletal muscle is the major deposit of protein molecules. As for any cell or tissue, total muscle protein reflects a dynamic turnover between net protein synthesis and degradation. Noninvasive and invasive techniques have been applied to determine amino acid catabolism and muscle protein building at rest, during exercise and during the recovery period after a single experiment or training sessions. Stable isotopic tracers (13C-lysine, 15N-glycine, ²H5-phenylalanine) and arteriovenous differences have been used in studies of skeletal muscle and collagen tissues under resting and exercise conditions. There are different fractional synthesis rates in skeletal muscle and tendon tissues, but there is no major difference between collagen and myofibrillar protein synthesis. Strenuous exercise provokes increased proteolysis and decreased protein synthesis, the opposite occurring during the recovery period. Individuals who exercise respond differently when resistance and endurance types of contractions are compared. Endurance exercise induces a greater oxidative capacity (enzymes) compared to resistance exercise, which induces fiber hypertrophy (myofibrils). Nitrogen balance (difference between protein intake and protein degradation) for athletes is usually balanced when the intake of protein reaches 1.2 g·kg-1·day-1 compared to 0.8 g·kg-1·day-1 in resting individuals. Muscular activities promote a cascade of signals leading to the stimulation of eukaryotic initiation of myofibrillar protein synthesis. As suggested in several publications, a bolus of 15-20 g protein (from skimmed milk or whey proteins) and carbohydrate (± 30 g maltodextrine) drinks is needed immediately after stopping exercise to stimulate muscle protein and tendon collagen turnover within 1 h.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Proteínas en la Dieta
/
Ejercicio Físico
/
Músculo Esquelético
/
Atletas
/
Ingesta Diaria Recomendada
/
Aminoácidos Esenciales
/
Proteínas Musculares
Límite:
Humanos
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
2012
Tipo del documento:
Artículo
País de afiliación:
Bélgica
/
Brasil
Institución/País de afiliación:
Free University of Brussels/BE
/
Instituto Vita/BR
/
Universidade de São Paulo/BR
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