Evaluation of the mean platelet volume in patients with cardiac syndrome X
Clinics
;
67(9): 1019-1022, Sept. 2012. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-649379
ABSTRACT
OBJECTIVE:
Cardiac syndrome X is characterized by angina-lke chest pain, a positive stress test, and normal coronary arteries. A patient's mean platelet volume, which potentially reflects platelet function and activity, is associated with coronary atherosclerosis and endothelial dysfunction. The aim of the present study was to evaluate the mean platelet volumes of patients with cardiac syndrome X, those with coronary artery disease and normal subjects.METHODS:
Two hundred thirty-six subjects (76 patients with cardiac syndrome X, 78 patients with coronary artery disease, and 82 controls) were enrolled in the study. All of the subjects were evaluated with a detailed medical history, physical examination, and biochemical analyses. The mean platelet volumes were compared between the three groups.RESULTS:
The mean platelet volumes in the patients with cardiac syndrome X and with coronary artery disease were significantly higher than those that were observed in the control group. There were no significant differences in the mean platelet volumes between the cardiac syndrome X and the coronary artery disease groups.CONCLUSION:
We have established that patients with cardiac syndrome X and coronary artery disease exhibit higher mean platelet volumes compared to controls. Patients with cardiac syndrome X exhibited higher mean platelet volumes compared to the controls, reflecting the presence of subclinical atherosclerosis. These findings suggest that, in addition to endothelial dysfunction, the presence of atherosclerosis may also contribute to the etiopathogenesis of cardiac syndrome X.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Plaquetas
/
Enfermedad de la Arteria Coronaria
/
Angina Microvascular
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Clinics
Asunto de la revista:
Medicina
Año:
2012
Tipo del documento:
Artículo
País de afiliación:
Turquía
Institución/País de afiliación:
Beytepe Military Hospital/TR
/
Gelibolu Military Hospital/TR
/
Gulhane Military Medical Academy/TR
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