Your browser doesn't support javascript.
loading
Etiologic and epidemiologic analysis of hand, foot, and mouth disease in Guangzhou city: a review of 4,753 cases
Zou, Xiao-ni; Zhang, Xiao-zhuang; Wang, Bo; Qiu, Yi-teng.
  • Zou, Xiao-ni; Maternal and Children Hospital of Guangdong Province. Department of Infection Control. Guangzhou. CN
  • Zhang, Xiao-zhuang; Maternal and Children Hospital of Guangdong Province. Department of Pediatrics. Guangzhou. CN
  • Wang, Bo; Maternal and Children Hospital of Guangdong Province. Department of Pediatrics. Guangzhou. CN
  • Qiu, Yi-teng; Maternal and Children Hospital of Guangdong Province. Department of Pediatrics. Guangzhou. CN
Braz. j. infect. dis ; 16(5): 457-465, Sept.-Oct. 2012. ilus, tab
Artículo en Inglés | LILACS | ID: lil-653435
ABSTRACT

OBJECTIVES:

This study aimed to review etiological and epidemiological data for hand, foot, and mouth disease (HFMD) cases that occurred between 2008 and 2010 in Guangzhou City, to help develop and implement precautionary measures applicable for future outbreaks.

METHODS:

The characteristics of 4,753 HFMD episodes were retrospectively reviewed in 4,636 patients reported between 2008 and 2010 by the Guangdong Women and Children's Hospital, which is the national enterovirus monitoring agent and the designated hospital in China for treating severe HFMD.

RESULTS:

Out of 4,753 incident episodes reviewed, 525 patients were hospitalized; 60% were males. Most patients (93.8%) were children under 5 years old, with a median age at onset of 2.4 years. HFMD incidence peaked in April/May and September/October. From the total, 1,067 (22.4%) infections were positive for human enterovirus 71 (HEV71), 1,094 (23.0%) were positive for coxsackievirus A16 (CA16), and 941 (19.8%) were positive for other common enteroviruses. In contrast, 1,666 (35.0%) cases were negative to HEV71, CA16, and other common enteroviruses. Cross-correlation coefficients demonstrated associations between the number of cases, seasonal temperatures, and humidity. Among hospitalized cases, HEV71 was positive in 261 (24.5%), and 42 (3.9%) critical cases were positive for HEV71.

CONCLUSION:

Seasonal fluctuations and HEV71 and CA16 were the two key factors influencing the Guangzhou HFMD epidemic. The infection predominantly affected children younger than 5 years old.
Asunto(s)


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Enfermedad de Boca, Mano y Pie Tipo de estudio: Estudio de etiología / Estudio de incidencia / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Child, preschool / Femenino / Humanos / Lactante / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Braz. j. infect. dis Asunto de la revista: Enfermedades Transmisibles Año: 2012 Tipo del documento: Artículo / Documento de proyecto País de afiliación: China Institución/País de afiliación: Maternal and Children Hospital of Guangdong Province/CN

Similares

MEDLINE

...
LILACS

LIS


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Enfermedad de Boca, Mano y Pie Tipo de estudio: Estudio de etiología / Estudio de incidencia / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Child, preschool / Femenino / Humanos / Lactante / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Braz. j. infect. dis Asunto de la revista: Enfermedades Transmisibles Año: 2012 Tipo del documento: Artículo / Documento de proyecto País de afiliación: China Institución/País de afiliación: Maternal and Children Hospital of Guangdong Province/CN