Functional evaluation indicates physical losses after hematopoietic stem cell transplantation
Rev. bras. hematol. hemoter
;
34(5): 345-351, 2012. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-654975
ABSTRACT
OBJECTIVE:
To perform a function evaluation of patients before and after hematopoietic stem cell transplantation.METHODS:
From November 2008 to November 2010, 29 female (58%) and 21 male patients (42%) with median age of 48 years (range 24-67) were enrolled in this study. Data collection was performed before and after autologous or allogeneic hematopoietic stem cell transplantation. Evaluation instruments included the 2-minute walking test to evaluate gait performance with assessment of the oxygen saturation, heart rate and Borg Scale before and after the test; grip strength for strength evaluation, Schober Test for spine mobility testing and maximum and adapted activity scores of the Human Activity Profile questionnaire to test functionality in daily activities.RESULTS:
Fifty patients were evaluated at baseline; six did not undergo hematopoietic stem cell transplantation (three died, one refused and two were excluded). Thus 44/50 (88% - 21 allogeneic and 23 autologous) transplantations were performed. Only 33 of the 44 patients (75%) performed evaluations after transplantation (nine died and two were excluded). Of the patients who performed both evaluations, significantly lower values were found in the evaluation after transplantation for the 2-minute walking test (p-value = 0.004), grip strength of both right and left hands (p-value = 0.004 and p-value < 0.0001, respectively), the Schober Test, and maximum and adapted activity scores (p-value < 0.0001). The heart rate was higher (p-value = 0.01) before the 2-minute walking test and oxygen saturation was higher (p-value = 0.02) after.CONCLUSION:
Statistical differences indicate functional impairment after transplantation showing physical losses in this population.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Examen Físico
/
Rehabilitación
/
Trasplante de Células Madre Hematopoyéticas
Límite:
Adolescente
/
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Rev. bras. hematol. hemoter
Asunto de la revista:
Hematología
Año:
2012
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Estadual de Campinas/BR
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