Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
Rev. bras. farmacogn
;
23(1): 145-152, Jan.-Feb. 2013. graf, tab
Artículo
en Inglés
| LILACS
| ID: lil-666174
ABSTRACT
Aqueous extract from seeds of Syzygium cumini (L.) Skeels, Myrtaceae, obtained by dynamic maceration was spray-dried and characterized by its physico-chemical and antihyperglycaemic action. The extract showed to possess high amount of polyphenols, significant in vitro free radical scavenger activity using the DPPH method and an antihyperglycaemic effect in alloxan-induced experimental diabetes. S. cumini spray-dried extracts were obtained using silicon dioxide and cassava starch as adjuvants. The powders showed acceptable flowability, compactability, and low hygroscopicity at 43% relative humidity. Besides, the spray-dried extracts showed in vivo antihyperglycaemic and in vitro scavenger activity comparable to the lyophilized extract. Thus, experimental data indicates that the extract from S. cumini has a relevant activity and that spray-drying could be adequately used to perform the technological processing of S. cumini fluid extracts.
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Índice:
LILACS (Américas)
Idioma:
Inglés
Revista:
Rev. bras. farmacogn
Asunto de la revista:
Farmacia
Año:
2013
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de São Paulo/BR
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