Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama / Influence of nutritional status, hormones serum levels, and family history on breast cancer development
Rev. méd. Chile
;
140(10): 1263-1267, oct. 2012. ilus, tab
Artículo
en Español
| LILACS
| ID: lil-668698
ABSTRACT
Background:
Several studies have analyzed the relation between obesity and the hormonal imbalances generated by overweight and a family history of breast cancer. All of these factors are potentially implicated in the early development of breast cancer.Aim:
To verify the existence of a significant relation between the nutritional status of breast cancer patients, their hormone serum levels (estrogens, prolactin, and progesterone), and the existence of a family history of breast cancer. Material andMethods:
Retrospective data was collected from clinical records of524 women diagnosed with breast cancer in a Spanish hospital.Results:
There was a positive association between estrogen, progesterone and prolactin serum levels and body mass index. The elevations in hormone levels occurred earlier in life among women with a family history of breast cancer. A two way ANOVA found a significant association between progesterone and prolactin levels with the age at diagnosis of breast cancer.Conclusions:
Extreme serum levels of these hormones appear to be related to the early development of breast cancer, which in turn is influenced by the existence of a family history of cancer among those women with normal or average hormone levels.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Progesterona
/
Prolactina
/
Neoplasias de la Mama
/
Estado Nutricional
/
Estrógenos
/
Obesidad
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Femenino
/
Humanos
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2012
Tipo del documento:
Artículo
País de afiliación:
España
Institución/País de afiliación:
Universidad de Granada/ES
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