Nonfatal demyelinating encephalomyelitis induced by coronavirus (JHM strain) infection in mice
Braz. j. med. biol. res
;
22(1): 77-80, 1989. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-67485
ABSTRACT
C3H mice infected intravenously with the JHM strain of coronavirus showed high incidence of demyelination (44.8%) and low incidence of encephalitis-induced mortality (6.9%). High titers of virus were detectable in the brain and liver of mice only during the first 3 to 12 days of infection (10 and 10 PFU/g, respectively). Most of the animals recovered from the first phase of disease and some (1.1%) came down with paralysis 6 to 7 weeks after the infection, with no histological changes or virus detectable in their tissues
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Índice:
LILACS (Américas)
Asunto principal:
Enfermedades Desmielinizantes
/
Infecciones por Coronavirus
/
Coronaviridae
/
Encefalomielitis
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1989
Tipo del documento:
Artículo
/
Congreso y conferencia
/
Documento de proyecto
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