Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
Biol. Res
;
46(1): 39-45, 2013. ilus
Artículo
en Inglés
| LILACS
| ID: lil-676819
ABSTRACT
Carotenoids are efficient antioxidants that are of great importance for human health. Lutein and zeaxanthin are carotinoids present in high concentrations in the human retina which are involved in the photoprotection of the human eye. Lutein may also protect the skin from ultraviolet (UV)-induced damage. The present study investigated the protective effect of lutein extracted from yellow silk cocoons of Bombyx mori on human keratinocytes against UVB irradiation. A human keratinocyte cell line and primary human keratinocytes were used to investigate the UVB protection effects of silk lutein and plant lutein. Silk lutein showed no cytotoxicity to keratinocytes. Treatment with silk lutein prior to UVB irradiation enhanced cell viability and cell proliferation, and reduced cell apoptosis. The protective effects of silk lutein may be superior to those of plant lutein. Silk lutein may have a benefit for protection of keratinocytes against UVB-irradiation.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Protectores contra Radiación
/
Rayos Ultravioleta
/
Luteína
/
Queratinocitos
/
Seda
Límite:
Animales
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Biol. Res
Asunto de la revista:
Biologia
Año:
2013
Tipo del documento:
Artículo
País de afiliación:
Tailandia
Institución/País de afiliación:
Naresuan University/TH
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