Assessment of the effectiveness of the PPD-mallein produced in Brazil for diagnosing glanders in mules
Braz. j. microbiol
;
44(1): 179-188, 2013. ilus
Artículo
en Inglés
| LILACS
| ID: lil-676903
ABSTRACT
To assess the potency of the PPD-mallein produced in Brazil, five animals were from a property identified as a focus of glanders. These animals had suggestive clinical signs of the disease and the other five, from a property free from glanders, showed no clinical signs and were serology negative (control group). PPD-mallein from Burkholderia mallei was obtained by precipitation with trichlo-roa-cetic acid and ammonium sulfate. The animals were inoculated according to the criteria established by Department of Agriculture, Livestock and Supply (MAPA) for the diagnosis of glanders. After 48 h of application of PPD-mallein, there was swelling in the area of application, presence of ocular secretion and tears in sick animals. The control group showed no inflammatory reaction at the site of inoculation of PPD-mallein. This immunogen produced in Brazil and still being tested was effective for identifying the infection in true positive animals and excluding the truly negative ones, being a new possibility for diagnosis and control of glanders.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Tricloroetanos
/
Ácidos
/
Vacunas Sintéticas
/
Equidae
/
Burkholderia mallei
/
Muermo
/
Sulfato de Amonio
/
Caballos
Tipo de estudio:
Estudio diagnóstico
/
Estudios de evaluación
/
Estudio pronóstico
Límite:
Animales
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Braz. j. microbiol
Asunto de la revista:
Microbiologia
Año:
2013
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Católica de Pernambuco/BR
/
Universidade Federal Rural de Pernambuco/BR
/
Universidade Federal de Alagoas/BR
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