Expression of FAS ligand in the ipsilateral and contralateral testicles of rats subjected to the torsion of the unilateral testicular cord
Acta cir. bras
;
28(7): 518-522, July 2013. ilus, graf, tab
Artículo
en Inglés
| LILACS
| ID: lil-679084
ABSTRACT
PURPOSE:
To investigate the expression of FAS ligand (FASL) in ipsilateral and contralateral testicles of rats submitted to ischemia/reperfusion.METHODS:
Wistar rats (n=21) distributed into groups control (GC), n=5, testicular exposure; ischemia (GI), (n=8), Torsion in the left testicular Cord (TCT) for three hours followed by orchiectomy without distortion and orchietomy of the contralateral testicle after 24 hours; and reperfusion (GR), (n=8), left TCT for 3 hours and distortion and repositioning on the scrotum and bilateral orchiectomy after 24 hours. Quantification of the FASL expression by immune-histochemistry.RESULTS:
Statistical analysis showed similarity between GC and GI (p>0.05), differences detected are concentrated on the GR (p<0.05), increase in immunoexpression of FASL in the subgroups Right GR (406.8+-61.5) and Left GR (135.3 +-28.9) with significant predominance in the GR subgroup.CONCLUSION:
Ischemia/reperfusion increased the FASL expression significantly in contralateral testicles in GR, in rats.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Torsión del Cordón Espermático
/
Testículo
/
Precondicionamiento Isquémico
/
Proteína Ligando Fas
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2013
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
UFMS/BR
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