Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats
Braz. arch. biol. technol
;
56(3): 377-382, May-June 2013. ilus
Artículo
en Inglés
| LILACS
| ID: lil-679184
ABSTRACT
This study aimed to evaluate the anti-inflammatory and repair effects of the ethanolic extract and ointment of Equisetum pyramidale on the skin lesions of rats induced to diabetes. After the induction of diabetes with alloxan, a surgical procedure was performed on the back of each rat. Then, they were separated into treatment groups G1 ethanol extract of E. pyramidale; G2-ointment (extract of E. pyramidale 80g + 20g of vaselinelanolin 11); G3 control (vehicle vaselinelanolin 11); and G4-no treatment during 3, 7 and 14 days. The samples were embedded in paraffin and stained with hematoxylin-eosin for histological analysis. The findings showed that the use of ethanolic extract as well as the ointment decreased the inflammatory cells at the site of inflammation, resulting a faster healing, with less crusting and lower amount of secretion in comparison to the control group. Therapy with topical herbal was an effective method in the inflammatory process of tissue repair, contributing to a faster and more organized tissue re-epithelialization.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Idioma:
Inglés
Revista:
Braz. arch. biol. technol
Asunto de la revista:
Biologia
Año:
2013
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Programa de Pós-Graduação em Saúde e Desenvolvimento da Região Centro-Oeste/BR
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