Decrease in hepatitis B prevalence among blood donors in Central-West Brazil
J. venom. anim. toxins incl. trop. dis
;
19: 7-7, maio 2013.
Artículo
en Inglés
| LILACS
| ID: lil-686613
ABSTRACT
Background:
The aim of the present study was to estimate hepatitis B virus seroprevalence among first-time blood donors in the city of Campo Grande, Mato Grosso do Sul State, in the central-western region of Brazil.Findings:
A retrospective analysis of first-time voluntary blood donor records, from January 2010 to December 2010, was conducted at the Hematology Center of Mato Grosso do Sul. The prevalence of the HBsAg and anti-HBc serological markers and their respective 95% confidence intervals were calculated. Chi-square analysis was performed between the seroprevalence previously found in 2001 and the one determined by the current study. Results were considered statistically significant if p < 0.05. Among 8,840 subjects, 269 (3.04%, 95% CI 2.7-3.4) were positive for HBV markers. The prevalence rate of HBsAg was 0.19% (95% CI 0.1-0.3) and anti-HBc alone was 2.85% (95% CI 2.5-3.2).Conclusions:
There was no statistically significant difference regarding gender. However, an important association was observed between HBV infection and older age (p < 0.01). The seroprevalence of HBV infection in first-time blood donors diminished from 2001 to 2010 (p < 0.01). Such decrease suggests an improvement in the recruitment of safe donors, the positive impact of vaccination programs and the decreasing of HBV infection prevalence in the general population.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Donantes de Sangre
/
Hepatitis B
Tipo de estudio:
Estudio de prevalencia
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
J. venom. anim. toxins incl. trop. dis
Asunto de la revista:
Toxicología
Año:
2013
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Federal University of Mato Grosso do Sul/BR
/
Mato Grosso do Sul Hematology Center/BR
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